| New names for pelvic pain could advance treatments
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| By
Penny Allen
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| Past terminology has held management back, Dr. Baranowski argued. The 'itis' of prostatitis, for example, has encouraged patients to seek anti-inflammatory or long-term antibiotic therapies that often don't help.
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| New test finds UTI cause in 45 minutes; 98% accurate
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| By
Patricia M. Fernberg
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| Los Angeles--A new biosensor technology that can identify the bacterial cause of urinary tract infections with 98% accuracy within 1 hour may help both clinicians and patients by closing the gap between diagnosis and appropriate treatment.
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| Genetics could explain chronic pelvic pain
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| By
Penny Allen
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| Baltimore?What causes chronic pain in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)? This could be the wrong question to ask, said Jeffrey S. Mogil, PhD, at the NIDDK-sponsored Chronic Pelvic Pain/Chronic Prostatitis Scientific Workshop. The better question may be: Why do these particular men have chronic pain, whereas others do not?
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| IL-8 may offer early tool for finding nosocomial UTI
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| By
Lawrence M. Prescott, PhD
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| Washington--Results from a small study demonstrate that urinary interleukin-8 (IL-8) can be used as an early diagnostic tool for nosocomial urinary tract infections, Mexican infectious disease specialists said during a presentation at the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy here. IL-8 appears to offer a faster alternative to quantitative cultures, according to the researchers.
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| Data find increase in UTIs caused ESBL-E coli
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| By
Lawrence M. Prescott, PhD
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| Washington--Over a 5-year study period, researchers have documented a significant increase of extended-spectrum beta-lactamases producing Escherichia coli (ESBL-E coli) isolated from urinary tract infections in both hospital and community settings.
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| Opiate use in nonmalignant pain: Not a simple dichotomy
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| By
Penny Allen
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| The use of opiates in chronic nonmalignant pain has its share of proponents and opponents among urologists who specialize in chronic pelvic pain.
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| 'Significant' link found between ED, heart disease
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| By
Mary Beth Nierengarten
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| San Antonio--Recently published prospective evidence strongly supports the growing recognition among physicians that erectile dysfunction may be a sign of future cardiovascular disease in some men.
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| Clinicians urged to adopt new model of chronic pain
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| By
Penny Allen
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| Baltimore--Scientific thinking about pain in general and chronic pain in particular has changed drastically in the last 50 years. Providers who treat chronic pain syndrome, such as chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), need to discard the old models if they are going to help patients.
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| E coli 'magic bullet' continues to elude scientists
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| By
Charles Bankhead
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| Washington--Increasing rates of fluoroquinolone-resistant urinary isolates of Escherichia coli have occurred against a backdrop of genetic variability, as no predominant variant has emerged as the principal culprit in resistance, according to a study of medical centers across the United States and Canada.
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| Second oral agent is approved for advanced RCC
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| By
Cheryl Guttman Krader
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| New York--The FDA has granted approval of oral sunitinib malate (Sutent), a multi-targeted receptor tyrosine kinase inhibitor, for the treatment of advanced renal cell carcinoma. The approval came after a priority review and was based on results from two phase II clinical trials dem-onstrating impressive drug activity measured by high partial response rates and delay to disease progression. It marks the second FDA approval of a drug for advanced RCC in as many months.
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| Data suggest sources of chronic, acute pain differ
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| By
Penny Allen
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| Baltimore--As the focus on pelvic pain syndromes moves away from the organs to the nervous system, researchers such as Ursula Wesselmann, MD, PhD, are trying to find out how acute pain develops into chronic pain.
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| Urine test boosts detection of recurrent bladder cancer
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| By
Lisette Hilton
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| Rochester, NY--A point-of-care assay that measures the nuclear matrix protein NMP22 in urine significantly improves detection of recurrent bladder cancer when used with cystoscopy, according to a new study.
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| E coli urinary isolates likely multi-drug resistant
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| By
Charles Bankhead
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| Washington--Outpatient urinary isolates of Escherichia coli that exhibit resistance to a fluoroquinolone antibiotic are likely to be resistant to multiple classes of antibiotics, results of a large North American laboratory study suggest.
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| Pelvic pain shows range of effects on sexual function
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| By
Penny Allen
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| In one study, 85% of the CP/CPPS patients had decreased frequency of sexual contact because of their pain, 67% said it interfered with or ended relationships, and 43% said it inhibited forming new relationships.
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| Neurophysiologic tests for CP/CPPS show promise
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| By
Penny Allen
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| Baltimore?Someday, you may be using neurophysiologic testing for follow-up and possibly even diagnosis of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) before you turn to the four-glass or modified test. That's because, increasingly, CP/CPPS is being recognized not as a disorder of the prostate, but as a neurologic disorder?a chronic pain syndrome that may begin in the viscera, but becomes a nervous system disorder as pain is centralized.
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| Psychological therapies may benefit CP/CPPS patients
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| By
Penny Allen
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| Baltimore--Psychological treatment, particularly cognitive behavioral therapy, can help ease chronic pain. That's why these therapies may be able to do the same for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) patients, argued Judith Turner, PhD, at the NIDDK-sponsored Chronic Pelvic Pain/Chronic Prostatitis Scientific Workshop here.
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