http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Article/list/9840 Treatment and research news about UTIs, interstitial cystitis, prostatitis, and more. 2009-11-21T09:04:10Z http://urologytimes.modernmedicine.com/urologytimes/Modern+Medicine+Now/Nerve-growth-factor-level-may-be-marker-for-neurog/ArticleStandard/Article/detail/637937?contextCategoryId=9840&ref=25 Nerve growth factor levels in urine could prove a useful biomarker for interstitial cystitis/painful bladder syndrome and neurogenic overactive bladder. 2009-11-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/442009/637937null XML http://urologytimes.modernmedicine.com/urologytimes/Modern+Medicine+Now/Research-points-to-expanding-role-of-botulinum-tox/ArticleStandard/Article/detail/637943?contextCategoryId=9840&ref=25 In this interview, Michael B. Chancellor, MD, discusses using botulinum toxin for treating overactive bladder, BPH, interstitial cystitis, and other conditions. 2009-11-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/442009/637943null XML http://urologytimes.modernmedicine.com/urologytimes/Modern+Medicine+Now/New-tacks-in-botulinum-toxin-show-promise-in-inter/ArticleStandard/Article/detail/637941?contextCategoryId=9840&ref=25 Botulinum toxin A is proving to be valuable for relief of interstitial cystitis. 2009-11-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/442009/637941null XML http://urologytimes.modernmedicine.com/urologytimes/Modern+Medicine+Now/Bladder-pain-syndromeinterstitial-cystitis-researc/ArticleStandard/Article/detail/637920?contextCategoryId=9840&ref=25 Advances in the field of bladder pain syndrome/interstitial cystitis will improve the ability of the practicing urologist to help patients with this problem. 2009-11-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/442009/637920null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Research-points-to-expanding-role-of-botulinum-tox/ArticleStandard/Article/detail/638689?contextCategoryId=9840&ref=25 In this podcast, Dr. Phil Hanno interviews Dr. Michael Chancellor on the potential role of botulinum toxin in urology. 2009-11-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/452009/638689null REMOTE http://urologytimes.modernmedicine.com/urologytimes/Modern+Medicine+Now/Up-to-65-of-US-women-meet-interstitial-cystitispai/ArticleStandard/Article/detail/637938?contextCategoryId=9840&ref=25 A new study has found that between 3.4 and 7.9 million American women age 18 and over have symptoms consistent with IC/PBS. 2009-11-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/442009/637938null XML http://urologytimes.modernmedicine.com/urologytimes/Modern+Medicine+Now/New-research-links-LUTS-cardiometabolic-disorders/ArticleStandard/Article/detail/633610?contextCategoryId=9840&ref=25 Men with even mild lower urinary tract symptoms are at an increased risk of developing components of cardiometabolic disorders. 2009-10-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/422009/633610null XML http://urologytimes.modernmedicine.com/urologytimes/Modern+Medicine+Now/Brain-images-illuminate-pain-differences-in-CPCPPS/ArticleStandard/Article/detail/624488?contextCategoryId=9840&ref=25 Different areas of the brain are active in different chronic pain conditions, and now researchers have shown that those areas are distinctly different in patients with interstitial cystitis and chronic prostatitis/chronic pelvic pain syndrome. 2009-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/372009/624488null XML http://urologytimes.modernmedicine.com/urologytimes/Modern+Medicine+Now/CPCPPS-phenotypes-may-help-target-treatment/ArticleStandard/Article/detail/624474?contextCategoryId=9840&ref=25 Men with CP/CPPS who responded to treatment in two trials reported better quality of life, particularly physical quality of life, and better sexual functioning. 2009-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/372009/624474null XML http://urologytimes.modernmedicine.com/urologytimes/Modern+Medicine+Now/Dementia-drug-demonstrates-efficacy-safety-in-chro/ArticleStandard/Article/detail/624468?contextCategoryId=9840&ref=25 Recent research suggests similarities in the etiologic and pathogenetic mechanisms of chronic pelvic pain syndrome and other pain syndromes. 2009-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/372009/624468null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Dementia-drug-demonstrates-efficacy-safety-in-CPPS/ArticleStandard/Article/detail/624801?contextCategoryId=9840&ref=25 Dr. Jordan Dimitrakov discusses the use of memantine in chronic pelvic pain syndrome with Urology Times. 2009-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/372009/624801null REMOTE http://urologytimes.modernmedicine.com/urologytimes/Modern+Medicine+Now/Narrow-beam-cystoscopy-outshines-hydrodistention/ArticleStandard/Article/detail/593050?contextCategoryId=9840&ref=25 A new in-office flexible cystoscopy technique for interstitial cystitis assessment can reveal the same bladder abnormalities that cystoscopy and hydrodistention under general anesthesia do, according to Japanese researchers, whose work was published in the International Journal of Urology (2008; 15:1039-43). 2009-04-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/152009/593050null XML http://urologytimes.modernmedicine.com/urologytimes/Modern+Medicine+Now/New-treatment-approaches-on-the-horizon-for-inters/ArticleStandard/Article/detail/593043?contextCategoryId=9840&ref=25 In just the next few years, new ideas, treatments, and treatment guidelines will give urologists better tools to diagnose and treat IC. 2009-04-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/152009/593043null XML http://www.modernmedicine.com/modernmedicine/Urology/Urinary-tract-infection-pathogen-assay-Definitive-/ArticleStandard/Article/detail/557218?contextCategoryId=9840&ref=25 A diagnostic assay based on computer chip technology could allow clinicians—and perhaps patients—to identify urinary tract pathogens in 45 minutes or less and it might also determine antibiotic susceptibility. 2008-10-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/412008/557218null XML http://urologytimes.modernmedicine.com/urologytimes/News/Colon-plays-major-role-in-interstitial-cystitis-fl/ArticleStandard/Article/detail/552226?contextCategoryId=9840&ref=25 The colon is irritated by spicy food, which can cause a flare-up of symptoms in patients with interstitial cystitis. 2008-09-25T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/392008/552226null HTML http://www.modernmedicine.com/modernmedicine/Urology/Weight-gain-age-sex-predict-likelihood-of-lower-ur/ArticleStandard/Article/detail/548556?contextCategoryId=9840&ref=25 A disproportionate influence of fat mass accounts for the relationship between body mass index and lower urinary tract symptoms. 2008-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/372008/548556null XML http://www.modernmedicine.com/modernmedicine/Urology/Alpha-blockers-in-chronic-prostatitischronic-pelvi/ArticleStandard/Article/detail/548557?contextCategoryId=9840&ref=25 In a trial of alpha-blocker therapy for men with newly diagnosed chronic prostatitis/chronic pelvic pain syndrome, placebo and treatment groups had the same proportion of responders: 49 percent. 2008-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/372008/548557null XML http://www.modernmedicine.com/modernmedicine/Urology/Interstitial-cystitis-patients-show-marked-improve/ArticleStandard/Article/detail/543647?contextCategoryId=9840&ref=25 This clinical trial shows that alkalinization of lidocaine improves absorption into the bladder and that the therapy decreases interstitial cystitis pain. 2008-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/342008/543647null XML http://www.modernmedicine.com/modernmedicine/Prostate+Cancer/Studies-offer-hope-for-rapid-diagnosis-of-common-p/ArticleStandard/Article/detail/543674?contextCategoryId=9840&ref=25 Studies in urinary tract infections provided the foundation for rapid diagnosis of common urinary tract infection pathogens and opened windows into the mechanisms underlying chronic prostatitis and interstitial cystitis, two diseases characterized by their resistance to treatment. 2008-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/342008/543674null XML http://www.modernmedicine.com/modernmedicine/Urology/Urologic-pelvic-pain-Diagnosis-and-management/ArticleStandard/Article/detail/533973?contextCategoryId=9840&ref=25 Urologic pelvic pain is a debilitating condition that affects significant numbers of men and women during their lifetime. Diverse disease states, physiologic conditions, and lifestyle factors may cause or exacerbate pain, challenging diagnosis and treatment efforts. We outline the fundamentals of a multimodal approach to managing urologic pelvic pain. 2008-08-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/322008/533973/utce0808_cv1_15518_main_thumbnail.jpg http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/322008/533973null XML http://urologytimes.modernmedicine.com/urologytimes/Online+Only/IC-patients-show-marked-improvement-with-lidocaine/ArticleStandard/Article/detail/517605?contextCategoryId=9840&ref=25 Treatment options are few for interstitial cystitis patients, especially for those with refractory disease. Frustratingly, trial after trial of promising therapies have shown no real improvement compared with placebo. But yesterday, that changed with presentation of the results of a trial of intravesical alkalinized lidocaine. 2008-05-18T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/212008/517605null HTML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Studies-probe-pain-pathogen-origins-interactions/ArticleStandard/Article/detail/517412?contextCategoryId=9840&ref=25 In chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), two pivotal clinical trials "are going to have an immediate impact on the way you practice," said Anthony J. Schæffer, MD, professor and chairman of the department of urology at the Northwestern University Feinberg School of Medicine, Chicago. 2008-05-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/202008/517412null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/ICBPS-research-therapies-push-treatment-frontier/ArticleStandard/Article/detail/517416?contextCategoryId=9840&ref=25 In 2008, urology is focusing on interstitial cystitis/bladder pain syndrome (IC/BPS) in earnest, with important clinical trial results. 2008-05-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/202008/517416null XML http://urologytimes.modernmedicine.com/urologytimes/Enews/Company-halts-study-of-IC-drug-due-to-positive-res/ArticleStandard/Article/detail/511624?contextCategoryId=9840&ref=25 Urigen Pharmaceuticals has announced the early closure of its study of a drug known as URG101 due to positive, statistically significant interim analysis results in both the primary and all secondary endpoints. Top-line results of the interim analysis, which was planned at 50% enrollment, were previously released March 12. 2008-04-24T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/172008/511624null HTML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Investigational-agent-improves-interstitial-cystit/ArticleStandard/Article/detail/505274?contextCategoryId=9840&ref=25 An investigational bladder instillation appears to improve daytime pain in patients with painful bladder syndrome/interstitial cystitis in a single dose, according to interim results of a phase II study. 2008-03-27T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/132008/505274null HTML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Guidelines-direct-treatment-for-three-types-of-UTI/ArticleStandard/Article/detail/489173?contextCategoryId=9840&ref=25 Thomas Hooton, MD, discusses the Infectious Diseases Society of America guidelines on three common urologic infections. 2008-02-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/062008/489173null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Cyclosporine-shows-dramatic-results-in-severe-inte/ArticleStandard/Article/detail/475196?contextCategoryId=9840&ref=25 For the first time in years, patients with interstitial cystitis, especially those with the worst cases, may have an effective new treatment. 2007-12-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/482007/475196null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Does-post-neuromodulation-APF-signal-interstitial-/ArticleStandard/Article/detail/475197?contextCategoryId=9840&ref=25 Interstitial cystitis biomarkers didn't change with long-term neuromodulation in a surprising study. 2007-12-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/482007/475197null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/FDA-approves-injectable-treatment-for-complicated-/ArticleStandard/Article/detail/468956?contextCategoryId=9840&ref=25 The FDA has approved injectable doripenem (Doribax) for the treatment of complicated urinary tract infections, including pyelonephritis. Doripenem has demonstrated activity against a wide range of gram-positive and gram-negative bacteria, including Pseudomonas, that cause these serious infections, research has shown. 2007-11-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/442007/468956null HTML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Early-treatment-of-UTI-in-infants-may-not-prevent-/ArticleStandard/Article/detail/468960?contextCategoryId=9840&ref=25 Early and appropriate treatment of urinary tract infection, especially during the first 24 hours after the onset of symptoms, diminishes the likelihood of renal involvement during the acute phase of the infection, but does not prevent scar formation, researchers reported in Pediatrics (2007; 120:e922-e928). 2007-11-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/442007/468960null HTML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/FDA-approves-5-day-regimen-for-complicated-UTI-acu/ArticleStandard/Article/detail/461920?contextCategoryId=9840&ref=25 FDA has approved the use of the 5-day, once-daily regimen of levofloxacin (Levaquin), 750 mg IV and oral, for the treatment of complicated urinary tract infections and acute pyelonephritis. 2007-10-04T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/402007/461920null HTML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/NIH-to-sponsor-5-year-research-project-for-chronic/ArticleStandard/Article/detail/461929?contextCategoryId=9840&ref=25 The National Institute of Diabetes and Digestive and Kidney Diseases, along with several other National Institutes of Health divisions, said it will commit up to $7.5 million per year starting in the summer of 2008 for a 5-year project to study interstitial cystitis/painful bladder syndrome (IC/PBS), chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), and related conditions. 2007-10-04T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/402007/461929null HTML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/ED-premature-ejaculation-common-in-prostatitis-pat/ArticleStandard/Article/detail/453761?contextCategoryId=9840&ref=25 Sexual dysfunction is common in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), regardless of the type of CP/CPPS they have, according to two recent studies. 2007-09-06T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/352007/453761null HTML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Urologists-Please-teach-us-PCPs-about-zebras/ArticleStandard/Article/detail/454949?contextCategoryId=9840&ref=25 The specialist must be cognizant of the vast information base required of PCPs, who are masters of nothing, but knowers of all. 2007-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/362007/454949null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Primary-care-physicians-show-major-gaps-in-underst/ArticleStandard/Article/detail/454952?contextCategoryId=9840&ref=25 Primary care physicians show large deficits in familiarity with and knowledge of chronic prostatitis/chronic pelvic pain syndrome along with significant variability in their approaches to diagnosis and treatment. 2007-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/362007/454952null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Sexual-dysfunctions-common-in-CPCPPS-patients/ArticleStandard/Article/detail/454972?contextCategoryId=9840&ref=25 Sexual dysfunction is common in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), regardless of the type of CP/CPPS they have. 2007-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/362007/454972null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/CPCPPS-Data-show-evidence-of-HPA-axis-abnormality/ArticleStandard/Article/detail/454973?contextCategoryId=9840&ref=25 Similar to patients with other chronic pain conditions, men with chronic prostatitis/chronic pelvic pain syndrome have evidence of a hypothalamic-pituitary-adrenal-axis abnormality. 2007-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/362007/454973null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Biopsychosocial-factors-may-help-target-CPCPPS-tre/ArticleStandard/Article/detail/454971?contextCategoryId=9840&ref=25 Several novel biopsychosocial factors have been identified as significant independent predictors of lower quality of life in patients with chronic prostatitis/chronic pelvic pain syndrome, according to an analysis of data collected from men enrolled in the National Institutes of Health's Chronic Prostatitis Cohort Study. 2007-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/362007/454971null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Significant-comorbidities-are-missed-in-interstiti/ArticleStandard/Article/detail/449568?contextCategoryId=9840&ref=25 Patients with apparent interstitial cystitis need thorough workups, and they're not always getting them. 2007-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/332007/449568null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Messages-on-urologic-infection-can-be-put-into-pra/ArticleStandard/Article/detail/449575?contextCategoryId=9840&ref=25 Studies of urinary tract infection presented at the 2007 AUA annual meeting had important lessons for practicing urologists. 2007-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/332007/449575null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Metabolic-syndrome-and-LUTS-An-emerging-relationsh/ArticleStandard/Article/detail/444356?contextCategoryId=9840&ref=25 Increasing evidence has recently pointed toward a relationship between LUTS secondary to BPH and the presence of metabolic syndrome. This relationship has been supported by recent epidemiologic findings. 2007-08-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/302007/444356null XML http://urologytimes.modernmedicine.com/urologytimes/Pediatric+Urology/Study-Prophylactic-treatment-of-children-with-UTIs/ArticleStandard/Article/detail/442317?contextCategoryId=9840&ref=25 The use of prophylactic antibiotics after an initial urinary tract infection is not associated with reduced risk of recurrent UTIs, but is associated with an increased risk of resistant infections, according to a new study from the University of Pennsylvania Robert Wood Johnson Clinical Scholars Program, Philadelphia. 2007-07-19T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/292007/442317null HTML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Relationship-seen-between-chronic-inflammation-LUT/ArticleStandard/Article/detail/431390?contextCategoryId=9840&ref=25 Preliminary results from the REDUCE (REduction by DUtasteride of prostate Cancer Events) trial suggest a relationship between the degree of chronic inflammation and lower urinary tract symptoms, but not clinical prostatitis-like symptoms in the REDUCE population. 2007-06-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/232007/431390null XML http://urologytimes.modernmedicine.com/urologytimes/2007+AUA+News/Genes-in-pathogenic-iE-colii-may-suppress-not-exac/ArticleStandard/Article/detail/427967?contextCategoryId=9840&ref=25 Some patients may be especially susceptible to urinary tract infections, and some uropathogens may be particularly virulent. But that's not the whole story. Virulent bacteria, in fact, may actually change their hosts' immune systems to break through their defenses. 2007-05-19T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/202007/427967null HTML http://urologytimes.modernmedicine.com/urologytimes/Urology/Immunosuppressive-shows-potential-in-treating-seve/ArticleStandard/Article/detail/427777?contextCategoryId=9840&ref=25 It's been a long time since urologists have been able to offer interstitial cystitis patients anything new and effective, but that day may be here for patients with the most severe disease. 2007-05-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/202007/427777null XML http://urologytimes.modernmedicine.com/urologytimes/Urology/Basic-research-may-improve-approach-to-UTI-CPPS/ArticleStandard/Article/detail/427775?contextCategoryId=9840&ref=25 Basic research should soon bring urologists entirely new ways to thwart or treat urinary tract infection, which could be welcome eleventh-hour saves from the problem of antibiotic-resistant bacteria. 2007-05-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/202007/427775null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/History-of-trauma-common-in-women-with-chronic-pel/ArticleStandard/Article/detail/420297?contextCategoryId=9840&ref=25 Abuse history, other major trauma, and post-traumatic stress disorder are reported commonly in women with chronic pelvic pain, suggesting the importance of screening for post-traumatic stress disorder in these women, according to researchers at the University of North Carolina at Chapel Hill. 2007-04-19T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/162007/420297null HTML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Drug-therapies-for-PBSIC-continue-to-evolve/ArticleStandard/Article/detail/420451?contextCategoryId=9840&ref=25 With 183 drugs tied to painful bladder syndrome/interstitial cystitis and none hitting a home run, what should clinicians do? 2007-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/162007/420451null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Research-challenges-traditional-models-of-IC-pain/ArticleStandard/Article/detail/420455?contextCategoryId=9840&ref=25 Because almost 94% of painful bladder syndrome/interstitial cystitis patients experience pain in some part of their body, pain management is essential. 2007-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/162007/420455null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Experts-strive-to-comprehend-IC-Whats-in-a-name/ArticleStandard/Article/detail/415117?contextCategoryId=9840&ref=25 Bethesda, MD—Concepts of what interstitial cystitis is, what causes it, and how to treat it are changing. That was apparent with the tremendous infusion of new ideas from many specialties here at the 2006 International Symposium: Frontiers in Painful Bladder Syndrome and Interstitial Cystitis, sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases. Whether those concepts can change without changing the name of the disease, however, was a hotly debated question. 2007-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/132007/415117/ut0407_01-jumps-1_11586_thumbnail.jpg http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/132007/415117null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/IC-by-any-other-name-Consensus-is-needed-soon/ArticleStandard/Article/detail/420453?contextCategoryId=9840&ref=25 The lack of standardization and agreement [about what to call interstitial cystitis] are major impediments to the progress we all hope to see. 2007-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/162007/420453null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/PBSIC-incidence-causes-Studies-offer-some-clues/ArticleStandard/Article/detail/420454?contextCategoryId=9840&ref=25 Exactly what painful bladder syndrome/interstitial cystitis is, how many people have it, what the risk factors are, what its causes are, what its natural history is, and how it differs from other types of voiding dysfunction in men are questions still looking for answers. 2007-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/162007/420454null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Recurrent-UTIs-may-be-caused-by-self-infection/ArticleStandard/Article/detail/401896?contextCategoryId=9840&ref=25 San Francisco—One of the most frustrating problems for women with urinary tract infections is to complete apparently successful antibiotic treatment, only to have the infection reoccur. 2007-02-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/052007/401896null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Broad-spectrum-agent-may-be-option-for-resistant-U/ArticleStandard/Article/detail/401895?contextCategoryId=9840&ref=25 San Francisco—Community-acquired urinary tract infections are becoming increasingly difficult to treat in several countries due to the widespread increase in drug resistance. In Spain, isolated strains of Escherichia coli have become resistant to nearly all oral antimicrobials, reported Genoveva Yague III, MD, professor of microbiology at the University of Murcia Medical School, Murcia, Spain. 2007-02-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/052007/401895null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Couples-share-bacterial-microflora-study-confirms/ArticleStandard/Article/detail/401894?contextCategoryId=9840&ref=25 San Francisco—A recent study from Sweden has confirmed what many clinicians have suspected: couples routinely share bacterial microflora. In clinical terms, if one partner is treated for a urinary tract infection or similar complaint, the other partner is likely to serve as a reservoir to re-infect the treated person. 2007-02-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/052007/401894null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Long-term-care-Reservoir-for-quinolone-resistance/ArticleStandard/Article/detail/401897?contextCategoryId=9840&ref=25 San Francisco—A study at one of the largest health systems in Vancouver, British Columbia, has found that long-term care facilities have become a significant reservoir for resistance to fluoroquinolone antibiotics. The rise of resistance appears to be the result of the increased use of quinolones for empiric treatment of urinary tract infections and pneumonia in residents of these facilities. 2007-02-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/052007/401897null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Resistant-E-coli-endemic-in-humans-not-animals/ArticleStandard/Article/detail/401898?contextCategoryId=9840&ref=25 San Francisco—Farm animals often are implicated as the source of drug-resistant Escherichia coli and other pathogens in humans. In some cases, human outbreaks have been traced back to infected farm animals, but a recent study of such outbreaks in Iowa exonerates food herds as the source of resistant E. coli that are responsible for urinary tract infections. 2007-02-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/052007/401898null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Pathogenic-E-coli-may-spread-through-casual-contac/ArticleStandard/Article/detail/401899?contextCategoryId=9840&ref=25 San Francisco—How uropathogenic Escherichia coli spreads within families is a continuing question for both practicing urologists and researchers. It has long been known that sexual contact may spread specific strains. A new study examining members of a single family confirms that casual contact between family members and even pets can also contribute to the transmission of E. coli, leading to cystitis and possibly other urologic infections. 2007-02-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/052007/401899null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Drug-application-filed-for-complicated-UTIs-acute-/ArticleStandard/Article/detail/398397?contextCategoryId=9840&ref=25 A supplemental new drug application has been filed with the FDA to support the use of levofloxacin (Levaquin) tablets for a 5-day, 750 mg once-daily regimen for the treatment of adults with mild, moderate, and severe complicated urinary tract infections and acute pyelonephritis. 2007-01-18T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/032007/398397null HTML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/MRI-useful-in-identifying-colo-vesical-fistulas/ArticleStandard/Article/detail/381335?contextCategoryId=9840&ref=25 Preston, United Kingdom—MRI scans proved to be an effective way to diagnose colo-vesical fistula in patients in a small study from the United Kingdom. The MRI group was compared with a retrospective group of patients who had been previously treated for the condition. 2006-10-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/432006/381335null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Data-on-ED-LUTS-offer-unique-opportunity-for-urolo/ArticleStandard/Article/detail/377466?contextCategoryId=9840&ref=25 Several studies presented at the 2006 AUA annual meeting provided evidence of a relationship between erectile dysfunction and lower urinary tract symptoms, with some data showing that treatment of LUTS will improve ED and vice versa. Treating multiple conditions at once means that patients may be able to receive better overall care, but physicians must avoid simply treating symptoms and take a more global approach to patient care, according to Steven A. Kaplan, MD. In this Urology Times interview, Dr. Kaplan, professor of urology and chief of the Institute of Bladder and Prostate Health at Weill Cornell Medical College, Cornell University, New York, discusses current findings on the association between ED and LUTS and their implications for patient management. He was interviewed by UT Editorial Consultant Philip M. Hanno, MD, MPH, professor of urology at the University of Pennsylvania, Philadelphia. 2006-10-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/402006/377466null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Groups-issue-advisory-about-alpha-blockers-iris-sy/ArticleStandard/Article/detail/377465?contextCategoryId=9840&ref=25 Linthicum, MD—AUA has partnered with two leading ophthalmology groups to raise awareness that individuals with past or present use of an alpha-1 blocker may develop a condition known as intraoperative floppy iris syndrome (IFIS) while undergoing cataract surgery and should inform their ophthalmologist about such medication use so that appropriate surgical techniques can be used. 2006-10-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/402006/377465null XML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/FDA-approves-generic-ciprofloxacin-injection/ArticleStandard/Article/detail/369930?contextCategoryId=9840&ref=25 The FDA has approved several abbreviated new drug applications for generic versions of ciprofloxacin injection for bacterial infections, including urinary tract infections. 2006-09-07T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/362006/369930null HTML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Nanobacteria-may-be-present-in-prostate-disease/ArticleStandard/Article/detail/372143?contextCategoryId=9840&ref=25 Atlanta—Are nanobacteria involved in prostate disease? That question hasn't been settled, but evidence of these controversial organisms has been found in the prostates and serum of men with prostatic inflammation. 2006-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/372006/372143null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Direct-medical-costs-double-in-men-with-prostatiti/ArticleStandard/Article/detail/372157?contextCategoryId=9840&ref=25 Atlanta—Direct medical costs are nearly twice as much for men with chronic prostatitis as men without, and those costs are definitely because of the disease, an analysis of an HMO's cost data showed. 2006-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/372006/372157null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/CPCPPS-therapies-may-yield-long-sought-answers/ArticleStandard/Article/detail/372144?contextCategoryId=9840&ref=25 Research has begun to examine a range of novel treatment modalities, some with quite promising results. 2006-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/372006/372144null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Pollen-extract-improves-pain-in-men-with-CPCPPS/ArticleStandard/Article/detail/372158?contextCategoryId=9840&ref=25 Atlanta—Urologists can add one more alternative, plant-based medication to the list of intriguing possibilities for treating urologic disease. This one is a rye-pollen extract called Cernilton that showed promising results in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) in a preliminary, placebo-controlled study from Germany. 2006-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/372006/372158null XML http://www.modernmedicine.com/modernmedicine/Sexual+Dysfunction/PDE-5-inhibitors-show-efficacy-in-ED-and-LUTS/ArticleStandard/Article/detail/372160?contextCategoryId=9840&ref=25 Atlanta—Sometimes studies are more notable for the questions they raise than for the ones they answer. Kevin T. McVary, MD, professor of urology at Northwestern University Feinberg School of Medicine, Chicago, presented a study at the AUA annual meeting showing that the phosphodiesterase type-5 inhibitor sildenafil citrate (Viagra) improves both erectile function and lower urinary tract symptoms, but has no apparent effect on flow rates. 2006-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/372006/372160null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Tandem-therapies-help-relieve-CPCPPS-symptoms/ArticleStandard/Article/detail/372159?contextCategoryId=9840&ref=25 Atlanta—Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) has a huge impact on men's sexuality, but a combination of pelvic muscle trigger point release physiotherapy and relaxation training can go a long way toward improving sexual dysfunction in these men, said Rodney U. Anderson, MD, professor of urology, Stanford University School of Medicine, Stanford, CA. 2006-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/372006/372159null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Physical-activity-may-lower-risk-of-prostatitis/ArticleStandard/Article/detail/372142?contextCategoryId=9840&ref=25 Atlanta—Because prostatitis in African-American men is not well studied, University of Michigan researchers examined the prevalence and risk factors in African-American men in Genessee County, MI, with a surprising result. On the whole, the risk factors matched those reported for Caucasian populations, but men who were physically active had significantly decreased odds of having prostatitis in a study presented at the AUA annual meeting. 2006-09-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/372006/372142null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/History-of-abuse-common-in-female-patients-with-IC/ArticleStandard/Article/detail/366760?contextCategoryId=9840&ref=25 Atlanta—The idea that abuse plays a role in pelvic pain syndromes in women has been a controversial one. Now, another study is adding to that debate. 2006-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/342006/366760null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Comestibles-fan-IC-fires-dietary-guidance-advised/ArticleStandard/Article/detail/366763?contextCategoryId=9840&ref=25 Atlanta—Diet does make a difference in symptoms in patients with interstitial cystitis. Most IC patients and the urologists who specialize in treating them are aware that certain foods, beverages, and supplements exacerbate IC symptoms, and a few ease them. Evidence for this has been sketchy and anecdotal, and a study presented at the 2004 AUA annual meeting cast doubt on that common wisdom by demonstrating that instillation of solutions from pH 5 to 7.5 had no effect on symptoms. 2006-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/342006/366763null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Fluorescein-study-refutes-permeability-theory-of-I/ArticleStandard/Article/detail/367100?contextCategoryId=9840&ref=25 Atlanta—Although the etiology of interstitial cystitis is unknown, one of the most popular theories is that patients have especially permeable bladders that allow noxious substances through, eliciting pain and other symptoms. But a study of bladder permeability in IC patients presented at the AUA annual meeting here cast doubt on what has become almost common wisdom. 2006-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/342006/367100null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Stone-fragment-culture-may-guide-antimicrobial-Tx/ArticleStandard/Article/detail/366768?contextCategoryId=9840&ref=25 The take-home messages on infection/inflammation at the AUA annual meeting covered a spectrum of urological conditions, including stone disease, urinary tract infection, urethritis, and interstitial cystitis. Results from both clinical studies and laboratory research have potential implications for urologists in their evaluation and management of patients with these disorders, said Anthony J. Schaeffer, MD, Herman L. Kretschmer professor and chairman, department of urology, Feinberg School of Medicine, Northwestern University, Chicago. 2006-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/342006/366768null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Sacral-stimulation-for-IC-fails-the-test-of-time/ArticleStandard/Article/detail/367102?contextCategoryId=9840&ref=25 Atlanta—At a tertiary referral center in the Netherlands, long-term results of sacral neuromodulation for interstitial cystitis were disappointing, despite initial success. The study, presented here at the AUA annual meeting, adds to similar results presented last year by researchers at the Cleveland Clinic and, for some IC specialists, confirms their own experience. 2006-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/342006/367102null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Study-shows-route-of-bladder-antigens-to-lymph-tis/ArticleStandard/Article/detail/366773?contextCategoryId=9840&ref=25 Atlanta—Bladder antigens travel to local and distant lymphoid tissues and enter the circulation, where they can travel as far as the spleen, according to results of a new study from the Feinberg School of Medicine at Northwestern University, Chicago. The study, which the authors say is the first functional study of antigen trafficking from the bladder, may further researchers' understanding of bladder cancer immunotherapies and potentially aid in the development of a vaccine for urinary tract infections. 2006-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/342006/366773null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Recurrent-UTIs-may-be-tied-to-host-immune-suppress/ArticleStandard/Article/detail/366772?contextCategoryId=9840&ref=25 Atlanta—Evading host immune response may enable uropathogenic Escherichia coli (UPEC) to establish reservoirs in the bladder that lead to recurrent urinary tract infections, according to David Klumpp, PhD, assistant professor of urology at the Feinberg School of Medicine, Northwestern University, Chicago. 2006-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/342006/366772null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Five-compounds-show-potential-in-OAB-pain-syndrome/ArticleStandard/Article/detail/366771?contextCategoryId=9840&ref=25 Atlanta—Five new compounds—none an antimuscarinic and all in different classes—are showing potential for overactive bladder. They may also have applications in BPH, chronic prostatitis/chronic pelvic pain syndrome, and painful bladder syndrome/interstitial cystitis (PBS/IC). 2006-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/342006/366771null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Hyperbaric-oxygen-therapy-may-relieve-IC-symptoms/ArticleStandard/Article/detail/367101?contextCategoryId=9840&ref=25 Atlanta—Just breathe. Could that be the key to easing interstitial cystitis pain? 2006-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/342006/367101null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Chronic-prostatitischronic-pelvic-pain-syndrome-Th/ArticleStandard/Article/detail/352727?contextCategoryId=9840&ref=25 The traditional biomedical model that has driven our understanding of the etiology, diagnosis, and management of chronic prostatitis/chronic pelvic pain syndrome has failed to yield an effective treatment strategy for the majority of affected patients. But a tsunami of recent research has begun to show where the traditional etiologic model may be wrong and how our new understanding of the pathogenesis of the condition may lead to more effective therapy. 2006-07-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/conturo/262006/352727/CNTUR0706_CV1_9876_thumbnail.jpg http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/conturo/262006/352727null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/THC-analog-shows-promise-in-painful-bladder-syndro/ArticleStandard/Article/detail/333585?contextCategoryId=9840&ref=25 Atlanta—Intravesical administration of an agent that is chemically related to cannabis produces a positive response in laboratory rats and may be useful in patients with painful bladder syndrome/interstitial cystitis, investigators from the University of Pittsburgh reported at the AUA annual meeting. 2006-06-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/232006/333585null XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Drug-eluting-stents-may-help-manage-complications/ArticleStandard/Article/detail/333597?contextCategoryId=9840&ref=25 Brisbane, Australia—Intravesical instillation of certain drugs has proven to be safe in reducing stent-related symptoms in patients undergoing ureteroscopy, and drug-eluting stents could eventually become a new treatment paradigm for other urologic disorders, such as bladder cancer and interstitial cystitis, said John Denstedt, MD, professor of urology, University of Western Ontario, London, ON. Dr. Denstedt discussed current research in stent technology and prospects for the future in a presentation at the Urological Society of Australasia annual meeting here. 2006-06-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/232006/333597null XML http://urologytimes.modernmedicine.com/urologytimes/Enews/FDA-approves-new-delivery-system-for-IV-antibiotic/ArticleStandard/Article/detail/330492?contextCategoryId=9840&ref=25 The FDA recently approved a new delivery system for the antibiotic cefoxitin, which is indicated for the treatment of urinary tract infections, gynecologic infections (eg, pelvic inflammatory disease), and a number of other common infections. 2006-06-01T04:00:00Z HTML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/New-agents-to-fight-UTI-prostatitis-slow-to-emerge/ArticleStandard/Article/detail/328134?contextCategoryId=9840&ref=25 At the upcoming AUA annual meeting, urologists will see new concepts emerging from research in both urinary tract infection and prostatitis, but those will take some time to produce new therapies, cautioned Anthony J. Schaeffer, MD. 2006-05-15T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Pain-management-plays-more-prominent-role-in-inter/ArticleStandard/Article/detail/328131?contextCategoryId=9840&ref=25 Today, interstitial cystitis is being viewed more as a pain syndrome than as a bladder disease, and that new view is driving much of the research that urologists will hear about at this year's AUA annual meeting and beyond. It should also inform their approach to treatment until the cause and cure are discovered, according to Philip M. Hanno, MD. 2006-05-15T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Painful-bladder-syndrome-A-guide-to-evaluation-and/ArticleStandard/Article/detail/322902?contextCategoryId=9840&ref=25 With a diagnosis of exclusion, the goals of evaluation for painful bladder syndrome are to verify that the bladder is indeed the organ causing the symptoms and to rule out any other pathology that may be responsible. Options for treatment include oral agents, intravesical therapy, and surgical therapy, which are used alone or in combination. 2006-05-01T04:00:00Z XML http://urologytimes.modernmedicine.com/urologytimes/Enews/Quinolones-are-most-commonly-prescribed-class-for-/ArticleStandard/Article/detail/320802?contextCategoryId=9840&ref=25 Quinolones have surpassed sulfas as the most common class of antibiotics prescribed for isolated outpatient UTI in women, and this growth raises concerns about increases in resisitance, suggest the authors of an article published in the Archives of Internal Medicine (2006; 166:635-9). 2006-04-20T04:00:00Z HTML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/Company-acquires-rights-to-bladder-cancer-drug/ArticleStandard/Article/detail/317979?contextCategoryId=9840&ref=25 Valera Pharmaceuticals, Inc. has completed its acquisition of the new drug application and other assets associated with valrubicin (Valstar), an FDA-approved drug indicated for treatment of carcinoma in situ (CIS) of the bladder. 2006-04-06T04:00:00Z HTML http://urologytimes.modernmedicine.com/urologytimes/Inflammation+and+Infection/CDC-to-launch-IC-awareness-campaign/ArticleStandard/Article/detail/317977?contextCategoryId=9840&ref=25 This fall, the Centers for Disease Control and Prevention, Atlanta, selected the Interstitial Cystitis Association as its partner to manage and direct a 5-year campaign to increase awareness of interstitial cystitis among health care providers and patients. 2006-04-06T04:00:00Z HTML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/E-coli-urinary-isolates-likely-multi-drug-resistan/ArticleStandard/Article/detail/312288?contextCategoryId=9840&ref=25 Washington--Outpatient urinary isolates of Escherichia coli that exhibit resistance to a fluoroquinolone antibiotic are likely to be resistant to multiple classes of antibiotics, results of a large North American laboratory study suggest. 2006-03-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/New-names-for-pelvic-pain-could-advance-treatments/ArticleStandard/Article/detail/311750?contextCategoryId=9840&ref=25 Past terminology has held management back, Dr. Baranowski argued. The 'itis' of prostatitis, for example, has encouraged patients to seek anti-inflammatory or long-term antibiotic therapies that often don't help. 2006-03-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Opiate-use-in-nonmalignant-pain-Not-a-simple-dicho/ArticleStandard/Article/detail/311758?contextCategoryId=9840&ref=25 The use of opiates in chronic nonmalignant pain has its share of proponents and opponents among urologists who specialize in chronic pelvic pain. 2006-03-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Pelvic-pain-shows-range-of-effects-on-sexual-funct/ArticleStandard/Article/detail/311752?contextCategoryId=9840&ref=25 In one study, 85% of the CP/CPPS patients had decreased frequency of sexual contact because of their pain, 67% said it interfered with or ended relationships, and 43% said it inhibited forming new relationships. 2006-03-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Data-find-increase-in-UTIs-caused-ESBL-E-coli/ArticleStandard/Article/detail/311754?contextCategoryId=9840&ref=25 Washington--Over a 5-year study period, researchers have documented a significant increase of extended-spectrum beta-lactamases producing Escherichia coli (ESBL-E coli) isolated from urinary tract infections in both hospital and community settings. 2006-03-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/E-coli-magic-bullet-continues-to-elude-scientists/ArticleStandard/Article/detail/312287?contextCategoryId=9840&ref=25 Washington--Increasing rates of fluoroquinolone-resistant urinary isolates of Escherichia coli have occurred against a backdrop of genetic variability, as no predominant variant has emerged as the principal culprit in resistance, according to a study of medical centers across the United States and Canada. 2006-03-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Clinicians-urged-to-adopt-new-model-of-chronic-pai/ArticleStandard/Article/detail/311755?contextCategoryId=9840&ref=25 Baltimore--Scientific thinking about pain in general and chronic pain in particular has changed drastically in the last 50 years. Providers who treat chronic pain syndrome, such as chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), need to discard the old models if they are going to help patients. 2006-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/102006/311755/ut0306_CV_9155_thumbnail.jpg XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/New-test-finds-UTI-cause-in-45-minutes-98-accurate/ArticleStandard/Article/detail/311759?contextCategoryId=9840&ref=25 Los Angeles--A new biosensor technology that can identify the bacterial cause of urinary tract infections with 98% accuracy within 1 hour may help both clinicians and patients by closing the gap between diagnosis and appropriate treatment. 2006-03-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/IL-8-may-offer-early-tool-for-finding-nosocomial-U/ArticleStandard/Article/detail/311753?contextCategoryId=9840&ref=25 Washington--Results from a small study demonstrate that urinary interleukin-8 (IL-8) can be used as an early diagnostic tool for nosocomial urinary tract infections, Mexican infectious disease specialists said during a presentation at the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy here. IL-8 appears to offer a faster alternative to quantitative cultures, according to the researchers. 2006-03-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Neurophysiologic-tests-for-CPCPPS-show-promise/ArticleStandard/Article/detail/311749?contextCategoryId=9840&ref=25 Baltimore?Someday, you may be using neurophysiologic testing for follow-up and possibly even diagnosis of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) before you turn to the four-glass or modified test. That's because, increasingly, CP/CPPS is being recognized not as a disorder of the prostate, but as a neurologic disorder?a chronic pain syndrome that may begin in the viscera, but becomes a nervous system disorder as pain is centralized. 2006-03-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Inflammation+and+Infection/Data-suggest-sources-of-chronic-acute-pain-differ/ArticleStandard/Article/detail/311748?contextCategoryId=9840&ref=25 Baltimore--As the focus on pelvic pain syndromes moves away from the organs to the nervous system, researchers such as Ursula Wesselmann, MD, PhD, are trying to find out how acute pain develops into chronic pain. 2006-03-01T05:00:00Z XML