http://urologytimes.modernmedicine.com/urologytimes/Male+Infertility/Article/list/9401 Treatment and research news and developments about male infertility. 2009-11-21T08:35:36Z http://urologytimes.modernmedicine.com/urologytimes/Modern+Medicine+Now/Expanded-role-of-mTESE-heads-advances-in-infertili/ArticleStandard/Article/detail/593046?contextCategoryId=9401&ref=25 Increasingly, urologists are finding mTESE to be one of the most effective and elegant methods of retrieving sperm from the testes. 2009-04-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/152009/593046null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Comet-assay-may-predict-assisted-reproductive-tech/ArticleStandard/Article/detail/584396?contextCategoryId=9401&ref=25 There is a significant correlation between Comet assay results and the likelihood of pregnancy using ART. 2009-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/102009/584396null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Sperm-maturation-arrest-Better-late-than-early/ArticleStandard/Article/detail/584397?contextCategoryId=9401&ref=25 The likelihood of successful sperm extraction may be higher at later stage sperm maturation arrest (MA), according to a study conducted by researchers at Baylor College of Medicine, Houston that was presented at the American Society for Reproductive Medicine annual meeting. 2009-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/102009/584397null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Low-baseline-FSH-predicts-successful-clomiphene-Tx/ArticleStandard/Article/detail/584394?contextCategoryId=9401&ref=25 Researchers are trying to identify which oligospermic men will respond to the drug clomiphene citrate. 2009-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/102009/584394null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Varicocelectomy-response-rate-Pregnancy-predictor/ArticleStandard/Article/detail/584393?contextCategoryId=9401&ref=25 Men who respond quickly to varicocele repair have a better chance of fathering children than men who take longer to respond do. 2009-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/102009/584393null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Immunofluorescence-may-improve-microdissection-tes/ArticleStandard/Article/detail/584395?contextCategoryId=9401&ref=25 Injecting an immunofluorescent dye into the testes may eventually help clinicians locate individual sperm and improve the yield from microdissection testicular sperm extraction (mTESE), researchers from the University of Iowa, Iowa City, reported at the American Society for Reproductive Medicine annual meeting. 2009-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/102009/584395null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Study-More-urologists-needed-in-fertility-clinics/ArticleStandard/Article/detail/577869?contextCategoryId=9401&ref=25 Fertility clinics need more urologists, according to a study of male factor infertility information presented on fertility clinic web sites. 2009-02-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/052009/577869null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Popular-selective-serotonin-reuptake-inhibitor-may/ArticleStandard/Article/detail/577868?contextCategoryId=9401&ref=25 A recent prospective clinical trial found that the antidepressant paroxetine (Paxil) is associated with a five-fold increase in the risk of abnormal sperm DNA fragmentation as measured by terminal deoxynucleotidyl transferase mediated dUTP nick end labeling (TUNEL) score. 2009-02-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/052009/577868null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Fertility-preservation-lacking-in-male-cancer-pati/ArticleStandard/Article/detail/563879?contextCategoryId=9401&ref=25 Physician attitudes, actions at odds over preserving fertility in adolescent men with cancer. 2008-11-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/452008/563879null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Infertile-males-at-higher-risk-for-melanoma-prosta/ArticleStandard/Article/detail/563878?contextCategoryId=9401&ref=25 Risks of developing melanoma and prostate cancer are increased among those with a diagnosis of male factor infertility. 2008-11-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/452008/563878null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Varicocele-repair-works-by-reducing-oxidant-stress/ArticleStandard/Article/detail/563880?contextCategoryId=9401&ref=25 Varicocele repair supports the hypothesis that this operation may help to restore fertility by reducing oxidant stress. 2008-11-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/452008/563880null XML http://www.modernmedicine.com/modernmedicine/Urology/FSH-should-not-be-factor-in-mTESE-patient-selectio/ArticleStandard/Article/detail/557227?contextCategoryId=9401&ref=25 Elevated serum follicle-stimulating hormone does not predict a lower sperm retrieval rate for men with nonobstructive azoospermia undergoing microdissection tes­ticular sperm extraction, and should not be considered a contraindication for this fertility procedure. 2008-10-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/412008/557227null XML http://www.modernmedicine.com/modernmedicine/Urology/Hypoandrogenism-is-common-finding-in-infertile-men/ArticleStandard/Article/detail/553504?contextCategoryId=9401&ref=25 Hypoandrogenism is common among men with nonobstructive azoospermia, and even those with normospermia. 2008-10-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/392008/553504null XML http://www.modernmedicine.com/modernmedicine/In+the+OR/Hypotrophy-more-common-in-men-with-varicoceles/ArticleStandard/Article/detail/553503?contextCategoryId=9401&ref=25 Among infertile men, testicular hypotrophy is about twice as common in men with varicoceles as in those without varicoceles. 2008-10-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/392008/553503null XML http://www.modernmedicine.com/modernmedicine/Surgery/Survey-reveals-gaps-in-basic-knowledge-of-Peyronie/ArticleStandard/Article/detail/553495?contextCategoryId=9401&ref=25 While many US urologists claim to be experts in sexual medicine, few know how to treat Peyronie'd disease. 2008-10-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/392008/553495null XML http://www.modernmedicine.com/modernmedicine/Urology/Data-show-why-urologists-need-to-evaluate-infertil/ArticleStandard/Article/detail/543657?contextCategoryId=9401&ref=25 What role should urologists play in the evaluation and management of couples who have difficulty conceiving? 2008-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/342008/543657null XML http://urologytimes.modernmedicine.com/urologytimes/Enews/Minimally-invasive-treatment-improves-male-fertili/ArticleStandard/Article/detail/534932?contextCategoryId=9401&ref=25 A minimally invasive treatment for varicoceles can significantly improve a couple’s chances of achieving pregnancy, according to a study published in Radiology (2008; 248:540-9). The study, conducted at the University of Bonn in Germany, also found that the level of sperm motility prior to treatment is a key predictor of success. 2008-08-14T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/332008/534932null HTML http://urologytimes.modernmedicine.com/urologytimes/Enews/FDA-requests-warnings-on-fluoroquinolone-drugs/ArticleStandard/Article/detail/529330?contextCategoryId=9401&ref=25 Manufacturers of fluoroquinolone antimicrobial drugs have been notified by FDA that a boxed warning in the product labeling concerning the increased risk of tendinitis and tendon rupture is necessary. 2008-07-17T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/292008/529330null HTML http://urologytimes.modernmedicine.com/urologytimes/Enews/Company-receives-approvable-letter-for-hypogonadis/ArticleStandard/Article/detail/529331?contextCategoryId=9401&ref=25 Indevus Pharmaceuticals, Inc. has received an approvable letter from FDA for its long-acting depot preparation of testosterone undecanoate (Nebido), which is indicated for the treatment of male hypogonadism. 2008-07-17T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/292008/529331null HTML http://urologytimes.modernmedicine.com/urologytimes/Male+Infertility/Data-suggest-possible-link-between-male-infertilit/ArticleStandard/Article/detail/518418?contextCategoryId=9401&ref=25 Results of a study based on data from approximately 43,400 men show risks of developing melanoma and prostate cancer are increased among those with a diagnosis of male factor infertility, reported researchers from the University of California, San Francisco. 2008-05-21T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/212008/518418null HTML http://urologytimes.modernmedicine.com/urologytimes/Male+Infertility/Survey-Inadequate-fertility-response-for-male-adol/ArticleStandard/Article/detail/518419?contextCategoryId=9401&ref=25 Pediatric oncologists appear strongly motivated to preserve fertility in male adolescent cancer patients, although there remains a disconnect between their attitudes and practices with respect to referring patients for available services, according to results of the Survey for Preservation of Adolescent REproduction (SPARE) study. 2008-05-21T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/212008/518419null HTML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Research-illuminates-influences-on-male-fertility/ArticleStandard/Article/detail/517413?contextCategoryId=9401&ref=25 Increasingly, genetics is changing the way urologists diagnose and treat problems related to male infertility. As lab findings become clinical realities, andrologists and general urologists alike are finding their daily practices changed by advances in our understanding of the human genome. 2008-05-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/202008/517413null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Soy-in-diet-may-lower-sperm-concentration-male-fer/ArticleStandard/Article/detail/506906?contextCategoryId=9401&ref=25 Higher intakes of soy foods and soy isoflavones were associated with reduced sperm concentrations in a Harvard study. 2008-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/142008/506906null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Sperm-morphology-cant-predict-intrauterine-insemin/ArticleStandard/Article/detail/506899?contextCategoryId=9401&ref=25 Mounting evidence suggests that the appearance of sperm has little to do with its function. 2008-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/142008/506899null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Survey-Patients-are-uninformed-about-male-infertil/ArticleStandard/Article/detail/506907?contextCategoryId=9401&ref=25 Men who present with infertility issues and their partners are relatively uninformed about the causes and treatments of male infertility, a fact that may be attributable to urologists' failure to properly market their capabilities in this area of clinical practice. 2008-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/142008/506907null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Novel-use-of-technology-sparks-infertility-advance/ArticleStandard/Article/detail/506902?contextCategoryId=9401&ref=25 Two groups have taken innovative steps to match technology with important clinical problems: the microscope with NOA and the Whitaker test with EDO. 2008-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/142008/506902null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/One-azoospermic-sample-enough-after-vasectomy-to-c/ArticleStandard/Article/detail/506900?contextCategoryId=9401&ref=25 Data from studies on post-vasectomy clearance suggest that a single azoospermic sample submitted 16 weeks following vasectomy is sufficient to establish the success of the procedure and future sterility. 2008-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/142008/506900null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Novel-test-diagnoses-ejaculatory-duct-obstruction/ArticleStandard/Article/detail/506898?contextCategoryId=9401&ref=25 A novel modification of the Whitaker test using ejaculatory duct manometry shows promise for the diagnosis of ejaculatory duct obstruction. 2008-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/142008/506898null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Assays-useful-for-measuring-sperm-chromatin-qualit/ArticleStandard/Article/detail/506901?contextCategoryId=9401&ref=25 Routine semen analysis does not absolutely predict the quality of sperm chromatin, which may help to explain why it often fails to predict reproductive outcomes in infertile couples. 2008-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/142008/506901null XML http://urologytimes.modernmedicine.com/urologytimes/Male+Infertility/Post-vasectomy-home-sperm-test-receives-FDA-nod/ArticleStandard/Article/detail/505275?contextCategoryId=9401&ref=25 The FDA has approved SpermCheck Vasectomy (ContraVac, Inc., Charlottesville, VA), a diagnostic product that confirms men’s post-vasectomy sterility. The device will enable men to test their post-vasectomy fertility status at home, rather than returning to the physician’s office or a laboratory for confirmation. 2008-03-27T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/132008/505275null HTML http://urologytimes.modernmedicine.com/urologytimes/Male+Infertility/Choice-of-vaginal-lubricant-may-affect-sperm-motil/ArticleStandard/Article/detail/505265?contextCategoryId=9401&ref=25 When it comes to effects on sperm motility or chromatin integrity, the choice of vaginal lubricant appears to make a difference, researchers reported in Fertility & Sterility (2008; 89:375-9). 2008-03-27T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/132008/505265null HTML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Male-factor-infertility-testicular-cancer-linked/ArticleStandard/Article/detail/498997?contextCategoryId=9401&ref=25 Men with a history of infertility have a markedly increased risk of subsequently developing testicular cancer. 2008-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/092008/498997null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Infertile-men-could-be-at-risk-for-osteopenia/ArticleStandard/Article/detail/449569?contextCategoryId=9401&ref=25 While it does not affect the vast majority of male infertility patients, a subgroup of men with disrupted hormonal axes and/or hypogonadism should be worked up for the presence of osteopenia. 2007-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/332007/449569null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Post-vasectomy-sample-at-16-weeks-is-sufficient-to/ArticleStandard/Article/detail/449573?contextCategoryId=9401&ref=25 Urologists attending this year's AUA annual meeting benefited from a wealth of cutting-edge research on the diagnosis and treatment of male infertility. 2007-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/332007/449573null XML http://urologytimes.modernmedicine.com/urologytimes/Male+Infertility/Molecular-biology-reshaping-approach-to-infertilit/ArticleStandard/Article/detail/427779?contextCategoryId=9401&ref=25 Many standard laboratory techniques could soon become clinical practice for the diagnosis and treatment of male infertility. 2007-05-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/202007/427779null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Growth-factors-may-play-a-role-in-vasectomy-succes/ArticleStandard/Article/detail/420452?contextCategoryId=9401&ref=25 Growth factors may play a role in the micro-recanalization that can occur after vasectomy. 2007-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/162007/420452null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Infertile-men-with-varicoceles-have-fewer-Leydig-c/ArticleStandard/Article/detail/420457?contextCategoryId=9401&ref=25 Infertile men with varicoceles demonstrate reductions in Leydig cell count, along with compensatory hypertrophy and signs of oxidative stress. 2007-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/162007/420457null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Vasectomy-reversal-Tissue-sealants-superior-to-sut/ArticleStandard/Article/detail/420456?contextCategoryId=9401&ref=25 Vasovasostomy anastomosis that is reinforced by tissue sealants is significantly less time-consuming than standard suture techniques and less likely to leak, and certain glues perform better than others. 2007-04-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/162007/420456null XML http://urologytimes.modernmedicine.com/urologytimes/Enews/Male-fertility-may-be-compromised-in-hot-tub-users/ArticleStandard/Article/detail/411600?contextCategoryId=9401&ref=25 Spending time in hot tubs and even hot baths may lead to male infertility, according to new research from the University of California, San Francisco. However, researchers said halting such exposure may reverse the effects. 2007-03-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/112007/411600null HTML http://urologytimes.modernmedicine.com/urologytimes/Enews/Vasectomy-may-be-a-risk-factor-for-rare-form-of-de/ArticleStandard/Article/detail/407681?contextCategoryId=9401&ref=25 Researchers at Northwestern University’s Feinberg School of Medicine, Chicago, have discovered that men who have had a vasectomy may be at increased risk for developing primary progressive aphasia (PPA), an irreversible neurologic disorder that causes patients to lose the ability to use and comprehend words. 2007-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/092007/407681null HTML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Do-culture-type-duration-affect-sperm-motility/ArticleStandard/Article/detail/408864?contextCategoryId=9401&ref=25 New Orleans—While improvements in sperm motility are seen when sperm are incubated in media for extended periods, no guidelines have been established yet for the optimal duration of incubation and culture type. Investigators from the University of Michigan have addressed this issue and have made determinations that may help guide intracytoplasmic sperm injection. 2007-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/102007/408864null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Mens-dietary-habits-affect-their-infertility/ArticleStandard/Article/detail/408863?contextCategoryId=9401&ref=25 New Orleans—Men who are interested in fatherhood had better eat their fruits and vegetables and add soy to their diet. These dietary recommendations were recently shown to boost sperm quality in an observational study from the University of Rochester, Rochester, NY. 2007-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/102007/408863null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Prostate-biopsy-may-affect-semen-parameters/ArticleStandard/Article/detail/408862?contextCategoryId=9401&ref=25 New Orleans—Transrectal ultrasound-guided biopsy of the prostate appears to have an immediate impact on the semen parameters of reproductive-age men, according to findings from a small study from Beth Israel Medical Center, New York. However, these effects were transient in all but one patient. 2007-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/102007/408862null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/High-BMI-linked-to-reduced-inhibin-B-sperm-quality/ArticleStandard/Article/detail/408866?contextCategoryId=9401&ref=25 New Orleans—Men with high body mass index values have lower serum inhibin B levels, according to a report from Reproductive Biology Associates, Atlanta. The study's authors point out that additional research is needed to determine whether increased BMI affects men's fertility. 2007-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/102007/408866null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Sperm-retrieval-in-NOA-varicocele-patients-Side-ma/ArticleStandard/Article/detail/408867?contextCategoryId=9401&ref=25 New Orleans—When retrieving sperm from men with nonobstructive azoospermia (NOA) and associated varicocele, go for the testis on the right side. That's the bottom line advice of University of California, San Francisco investigators who evaluated whether side matters in retrieving sperm for ICSI. 2007-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/102007/408867null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Teratospermia-does-not-affect-IVFICSI-outcomes/ArticleStandard/Article/detail/408865?contextCategoryId=9401&ref=25 New Orleans—Having severe teratospermia does not affect pregnancy outcomes when using in vitro fertilization with intracytoplasmic sperm injection, according to a large retrospective review presented at the American Society for Reproductive Medicine annual meeting by investigators from Weill Medical College of Cornell University, New York. 2007-03-01T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/102007/408865null XML http://urologytimes.modernmedicine.com/urologytimes/Enews/Embolization-for-varicoceles-may-help-infertile-co/ArticleStandard/Article/detail/390402?contextCategoryId=9401&ref=25 In men with varicoceles, spermatic vein embolization can significantly improve the chances for pregnancy, German researchers suggest. 2006-12-07T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/492006/390402null HTML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Infertility-takes-psychological-toll-on-patients/ArticleStandard/Article/detail/377479?contextCategoryId=9401&ref=25 Atlanta—Two separate studies have found that men and women dealing with infertility suffer from depression and anxiety at a greater rate than the general population. 2006-10-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/402006/377479null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Surgery-more-accurate-in-finding-CF-linked-anomali/ArticleStandard/Article/detail/377477?contextCategoryId=9401&ref=25 Atlanta—Male patients who carry any of the 25 gene mutations related to cystic fibrosis (CF) may also have anomalies of the reproductive tract, including unilateral or bilateral absence of the vas deferens or epididymal obstruction. 2006-10-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/402006/377477null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Performing-vasectomy-reversal-Use-a-microscope/ArticleStandard/Article/detail/377478?contextCategoryId=9401&ref=25 Atlanta—If you're going to perform a vasectomy reversal, use a microscope. Despite the additional time and cost involved, microsurgical vasovasostomy is superior to the loupe-assisted macroscopic technique, findings from a recent study from Korea confirm. 2006-10-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/402006/377478null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Bilateral-varicocelectomy-improves-odds-of-pregnan/ArticleStandard/Article/detail/377480?contextCategoryId=9401&ref=25 Atlanta—Men whose infertility is due to varicocele may be able to improve the likelihood of achieving impregnation by undergoing bilateral, rather than unilateral varicocelectomy, when indicated. This was the conclusion of the authors of a Canadian study presented here at the AUA annual meeting. 2006-10-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/402006/377480null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Infertility-story-offers-a-lesson-for-all-urologis/ArticleStandard/Article/detail/377467?contextCategoryId=9401&ref=25 This story about the operating microscope and the vas has two morals. 2006-10-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/402006/377467null XML http://urologytimes.modernmedicine.com/urologytimes/Enews/Obesity-is-linked-to-infertility-in-men/ArticleStandard/Article/detail/373643?contextCategoryId=9401&ref=25 Men with increased body mass index are significantly more likely to be infertile than are normal-weight men, according to research conducted at the National Institute of Environmental Health Sciences and published in Epidemiology (2006; 17:520-3). 2006-09-21T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/382006/373643null HTML http://urologytimes.modernmedicine.com/urologytimes/Male+Infertility/Higher-paternal-age-influences-risk-of-miscarriage/ArticleStandard/Article/detail/365829?contextCategoryId=9401&ref=25 Independent of maternal age and multiple other factors, the odds of miscarriage are significantly higher in pregnancies conceived from fathers 40 years of age or older than from fathers under 25 years of age, according to the authors of a study published in Obstetrics & Gynecology (2006; 108:369-77). 2006-08-16T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/332006/365829null HTML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Research-sheds-light-on-genetic-basis-of-infertili/ArticleStandard/Article/detail/366766?contextCategoryId=9401&ref=25 From the genetic basis of male reproductive dysfunction to the psychology of those who suffer from it, men who experience infertility issues continue to benefit from research into all facets of the condition. 2006-08-15T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/342006/366766null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/VEGF-TP1-may-mark-presence-of-sperm-in-men-with-NO/ArticleStandard/Article/detail/357758?contextCategoryId=9401&ref=25 Chicago—A widely studied protein can help urologists find sperm to be used for in vitro fertilization and may even indicate another future pharmaceutical application of the substance, according to research presented here at the American Society of Andrology annual meeting here. 2006-07-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/282006/357758null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Test-may-help-measure-genetic-integrity-of-sperm/ArticleStandard/Article/detail/357759?contextCategoryId=9401&ref=25 Chicago—Two measures derived from an assay being used in research by the U.S. Environmental Protection Agency may add an indicator for the genetic health of sperm to those that already measure sperm count and sperm motility, according to a poster presented at the American Society of Andrology annual meeting here. 2006-07-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/282006/357759null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Microsurgical-vasectomy-reversal-Techniques-to-imp/ArticleStandard/Article/detail/352725?contextCategoryId=9401&ref=25 Microsurgical vasovasostomy and epididymovasostomy are effective means of vasectomy reversal for couples desiring fertility. The key to success—and the hard part—is meticulous reapproximation of the vasal or epididymal segments. 2006-07-01T04:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/conturo/262006/352725null XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Testosterone-replacement-therapy-Minimizing-its-im/ArticleStandard/Article/detail/330548?contextCategoryId=9401&ref=25 Testosterone replacement therapy is now being more widely used not only in older men who are likely to be past their childbearing years, but also in both younger and older men who may want to father a child. This article describes the potential negative effects of testosterone replacement on male fertility, provides an overview of the mechanisms behind them, and suggests possible regimens for combating male infertility in patients seeking paternity. 2006-06-01T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Genetics-playing-larger-role-in-male-infertility/ArticleStandard/Article/detail/328142?contextCategoryId=9401&ref=25 It's safe to say that when the sequencing of the human genome was completed in April 2003, the diagnosis and treatment of male infertility was turned on its ear. 2006-05-15T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Neural-network-model-helps-predict-fertility-succe/ArticleStandard/Article/detail/325491?contextCategoryId=9401&ref=25 Iowa City, IA—A neural network that takes into account maternal age, sperm retrieval technique, type of sperm used, and type of male factor has been found to be clinically useful for predicting the outcome of in vitro fertilization/intracytoplasmic sperm injection. 2006-05-01T04:00:00Z XML http://urologytimes.modernmedicine.com/urologytimes/Enews/Most-vasectomy-patients-fail-to-comply-with-follow/ArticleStandard/Article/detail/320801?contextCategoryId=9401&ref=25 One-fourth of men who undergo vasectomies forego having their semen tested to determine the procedure?s effectiveness, according to a Cleveland Clinic study. 2006-04-20T04:00:00Z HTML http://urologytimes.modernmedicine.com/urologytimes/Pediatric+Urology/Adolescent-cancer-patients-are-able-to-bank-sperm/ArticleStandard/Article/detail/312783?contextCategoryId=9401&ref=25 Most adolescent cancer patients who have been offered fertility preservation are able to bank sperm, according to a study published in the Archives of Disease in Childhood (2006; 91:149-52). 2006-03-16T05:00:00Z HTML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Inhibin-B-A-better-infertility-marker-than-FSH-or-/ArticleStandard/Article/detail/307327?contextCategoryId=9401&ref=25 Montreal--The level of inhibin B may be a better marker of male infertility than both the typically used follicle stimulating hormone (FSH) and luteinizing hormone (LH), according to new research. These findings have yet to be confirmed in a large, prospective trial, however. 2006-02-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/News/Anti-estrogen-may-benefit-some-men-with-idiopathic/ArticleStandard/Article/detail/307330?contextCategoryId=9401&ref=25 Montreal--The anti-estrogen agent clomiphene citrate (Clomid, Milophene, Serophene) may provide an easier, less expensive treatment for infertility among some men with hypogonadotropic hypo-gonadism [HH], according to a small retrospective study. The agent may be worth trying before the more expensive and difficult-to-administer gonadotropins are employed. 2006-02-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/News/Testis-biopsy-Integral-to-workup-of-infertile-men/ArticleStandard/Article/detail/307317?contextCategoryId=9401&ref=25 Montreal--Spermatogenesis markers that can be easily obtained from a noninvasive testis biopsy may predict which patients will respond to surgical varicocele repair. Testis biopsy, therefore, should be part of the regular workup for male infertility patients, suggest the authors of the 2005 Society for Male Reproduction and Urology Prize paper presented here at the American Society for Reproductive Medicine annual meeting. 2006-02-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/BMI-linked-with-changes-that-may-affect-fertility/ArticleStandard/Article/detail/307338?contextCategoryId=9401&ref=25 Montreal--Men with a body mass index indicative of being overweight or obese may exhibit changes in endocrine levels—notably lower testosterone levels—that could contribute to infertility, new research shows. It is possible, therefore, that fertility problems could be ameliorated with weight loss in some men. 2006-02-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Nonobstructive-azoospermia-is-tied-to-genetic-defe/ArticleStandard/Article/detail/307336?contextCategoryId=9401&ref=25 Montreal--Idiopathic, primary nonobstructive azoospermia (NOA) is linked to a genetic defect known as a dysfunctional DNA mismatch repair pathway that also places these men at increased risk for cancer and other medical illnesses. Given that the problem is genetic in origin, the consequences of this defect may be of significance for both patients and their offspring, researchers say. Both concerns require close monitoring by physicians. 2006-02-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/News/Vasectomy-reversal-Data-point-to-choice-of-techniq/ArticleStandard/Article/detail/307329?contextCategoryId=9401&ref=25 Montreal--As the controversy over whether to perform vasovasostomy or vasoepididymostomy for vasectomy reversal rages, two small studies have provided some new insight into when to choose one surgical technique over the other. One study demonstrates that expert surgeons can provide better results with vasoepididymostomy among patients with vasospermia, defined as no sperm in the vasal fluid, regardless of the condition of the vasal fluid. The second study suggests that the presence of sperm parts in the vasal fluid signals that vasovasostomy might be the better option. 2006-02-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Despite-drawbacks-TESE-derived-sperm-is-superior/ArticleStandard/Article/detail/307328?contextCategoryId=9401&ref=25 Montreal--Although testicular sperm extraction (TESE) may provide somewhat better pregnancy rates than the use of ejaculated sperm for intracytoplasmic sperm injection for men with low sperm counts, a higher-than-average proportion of abnormal sperm, or almost no sperm in the ejaculate, TESE does have important disadvantages. It is up to patients and their physicians to choose the appropriate procedure, based on individual circumstances and clinical features, researchers say. 2006-02-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Smoking-affects-sperms-ability-to-fertilize/ArticleStandard/Article/detail/307337?contextCategoryId=9401&ref=25 Montreal--In case your patients need another reason to quit, recent research indicates that smoking tobacco reduces the ability of sperm to fertilize an egg. There appears to be a dose-response relationship, with heavy smokers at greater risk for more severe impairment of sperm, according to a study presented at the American Society for Reproductive Medicine annual meeting here. It remains to be seen whether quitting smoking or even cutting down will lead to improvements in sperm functions that support fertilization. 2006-02-01T05:00:00Z XML http://urologytimes.modernmedicine.com/urologytimes/Male+Infertility/Age-continues-to-affect-assisted-reproductive-tech/ArticleStandard/Article/detail/284357?contextCategoryId=9401&ref=25 In 2003, more than 48,000 babies were born in the United States as a result of assisted reproductive technology (ART) procedures, according to a new report from the Centers for Disease Control and Prevention. This marks an increase from 45,751 babies in 2002. 2006-01-19T05:00:00Z HTML http://urologytimes.modernmedicine.com/urologytimes/Male+Infertility/Infertile-patients-at-higher-risk-for-testicular-c/ArticleStandard/Article/detail/254382?contextCategoryId=9401&ref=25 Men with infertility and abnormal sperm counts have a 20-fold greater incidence of testicular cancer than men in the general population, according to a study published in the Journal of Urology (2005; 174:1819-22). 2005-12-01T05:00:00Z HTML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Spermatogenesis-cycle-shorter-than-previously-thou/ArticleStandard/Article/detail/177459?contextCategoryId=9401&ref=25 Advances in the field of male infertility continue to provide insight into the factors and processes that make fertility possible. Ultimately, the advances lead to techniques that extend the possibility of fertility to an ever-increasing population of patients. 2005-08-15T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Test-is-found-sensitive-specific-for-Klinefelters/ArticleStandard/Article/detail/166521?contextCategoryId=9401&ref=25 San Antonio--Methylation-specific polymerase chain reaction (M-PCR) is a sensitive, specific, fast, and relatively inexpensive method of diagnosing Klinefelter syndrome, according to data presented here by Cornell University researchers. 2005-06-01T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/News+Feature/Advances-in-andrology-moving-quickly-into-practice/ArticleStandard/Article/detail/164411?contextCategoryId=9401&ref=25 It often takes years before medical advances make their way from the laboratory bench to the physician's office. Such is not the case in andrology. In many instances, the cutting edge will be of clinical relevance very soon for urologists who treat male infertility, according to Craig S. Niederberger, chief of andrology at the University of Illinois, Chicago. 2005-05-15T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/News/Paternity-rates-for-men-in-their-30s-increasing/ArticleStandard/Article/detail/144057?contextCategoryId=9401&ref=25 Philadelphia--The birth rate for all U.S. men increased for fathers aged 30 to 39 years and decreased for fathers aged 20 to 29 years between 1993 and 2002. For fathers aged 40 and above, the rate remained stable, according to a new analysis of the federal National Vital Statistics Report. 2005-01-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Frozen-fresh-sperm-show-similar-fertilization-rate/ArticleStandard/Article/detail/144061?contextCategoryId=9401&ref=25 Philadelphia--A new study shows that fertilization rates with cryopreserved sperm are not inferior to those with "fresh" sperm, although it will be several more years before researchers can determine whether the rates are equal in nature. 2005-01-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/ICSI-standard-IVF-show-similar-birth-defect-rates/ArticleStandard/Article/detail/144064?contextCategoryId=9401&ref=25 Philadelphia--The incidence of major malformations after intracytoplasmic sperm injection is similar to that of conventional in vitro fertilization pregnancies and terminations, according to new data from an Australian study. 2005-01-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/News/Vitamin-D-may-play-role-in-male-infertility/ArticleStandard/Article/detail/144056?contextCategoryId=9401&ref=25 Philadelphia--Vitamin D may play a role in sperm physiology and male infertility, according to findings from new basic research presented at the American Society for Reproductive Medicine 60th annual meeting. 2005-01-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Vasectomy-reversal-is-viable-for-long-term-blockag/ArticleStandard/Article/detail/144058?contextCategoryId=9401&ref=25 Philadelphia--Vasectomy reversal is a viable option for men who desire restoration of fertility despite obstructive intervals exceeding 14 years, according to the results of a study by Cleveland Clinic researchers. 2005-01-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Bladder%2C+Kidney%2C+and+Other+Urologic+Cancers/Sperm-banking-recommended-before-RT-for-testis-Ca/ArticleStandard/Article/detail/144073?contextCategoryId=9401&ref=25 Philadelphia--Men being treated with radiation therapy for testicular cancer should be encouraged to cryopreserve sperm, say authors of a small study presented at the American Society for Reproductive Medicine annual meeting. 2005-01-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/News/Transient-patency-is-a-problem-after-vasovasostomy/ArticleStandard/Article/detail/144063?contextCategoryId=9401&ref=25 Philadelphia--Even after vasovasostomy success, there is a chance that transient patency the "shutting down" of viable sperm production may occur, say researchers from the University of Alabama, Medical College of Wisconsin, and University of Iowa. 2005-01-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Bladder%2C+Kidney%2C+and+Other+Urologic+Cancers/Testicular-cancer-treatment-impairs-semen-quality/ArticleStandard/Article/detail/144072?contextCategoryId=9401&ref=25 Philadelphia--Treatment for testicular cancer caused the rates of severe oligozoospermia and azoospermia to rise from 7% to 27% and 0% to 12%, respectively, in a study that suggests a need for sperm banking in men treated for the disease. 2005-01-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Sperm-concentration-motility-decrease-as-men-age/ArticleStandard/Article/detail/137320?contextCategoryId=9401&ref=25 Caxias do Sul, Brazil--Men over the age of 40 years may have lower semen quality, but not necessarily lower sperm morphology. That's an important fact to remember when evaluating these men for infertility, suggests a study by Brazilian researchers. 2004-12-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/News/Rare-non-motile-sperm-points-to-vasectomy-success/ArticleStandard/Article/detail/129152?contextCategoryId=9401&ref=25 Toronto--Patients who show evidence of rare non-motile sperm after undergoing vasectomy will eventually become azoospermic—marking vasectomy success. However, patient compliance post-vasectomy remains low, despite aggressive pre- and postoperative counseling, University of Toronto researchers report. 2004-10-01T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/News/Modified-vasectomy-reversal-simplifies-technique/ArticleStandard/Article/detail/119867?contextCategoryId=9401&ref=25 Among the important research on male infertility presented at the 2004 AUA annual meeting, a new vasoepididymostomy technique and findings about the impact of long-term varicoceles on pregnancy rates took center stage, said Craig S. Niederberger, MD, chief of andrology at the University of Illinois, Chicago. This research, as well as data questioning the value of two widely used prognostic measures, provided the most significant take-home points for practicing urologists, he said 2004-08-15T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Stem-cells-may-shape-future-of-male-infertility-Tx/ArticleStandard/Article/detail/107233?contextCategoryId=9401&ref=25 San Francisco--Scientific and technical obstacles notwithstanding, stem cell transplantation has considerable potential for treatment of male infertility. 2004-08-01T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/Perspective/What-role-will-stem-cells-play-in-male-infertility/ArticleStandard/Article/detail/107237?contextCategoryId=9401&ref=25 The use of stem cells to treat otherwise incurable or serious human disease remains a political "hot potato." One must remember, however, that the sources of embryonic and adult stem cells are distinctly different. The use of adult stem cells avoids all of the ethical and political criticism associated with the former's fetal etiology. While not totipotential, adult stem cells still have the advantage of prolonged proliferation, self-renewal, generation of more differentiated cells, maintenance of developmental potential, and proliferation in response to injury. 2004-08-01T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/AUA+2004+News/Fresh-and-frozen-sperm-equally-efficacious-for-IVF/ArticleStandard/Article/detail/97494?contextCategoryId=9401&ref=25 San Francisco--It doesn't matter whether fresh or frozen sperm
 is used for in vitro fertilization, as both have equivalent outcomes in
 terms of fertilization rates, embryo quality, and the chance of having at
 least one live birth event, according to a Mayo Clinic study. 2004-06-01T04:00:00Z HTML http://www.modernmedicine.com/modernmedicine/Male+Infertility/DNA-integrity-studies-yield-key-findings-on-infert/ArticleStandard/Article/detail/93209?contextCategoryId=9401&ref=25 Most practicing urologists have little time to closely examine the basic
 science behind advances in male infertility, but the lab work that researchers
 are performing in this subspecialty today is poised to dramatically affect
 the way urology is practiced tomorrow. 2004-04-15T04:00:00Z HTML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Polishing-the-gold-standard-in-vasovasostomy/ArticleStandard/Article/detail/84508?contextCategoryId=9401&ref=25 San Antonio--Biomaterial wraps are a promising adjunct for vasovasostomy,
 according to results of an animal study that incorporated a biomaterial
 matrix and a sealant into the conventional three-suture anastomosis. Researchers
 called this "polishing the gold standard" because of the high
 patency rate of the standard procedure. 2004-02-01T05:00:00Z HTML http://www.modernmedicine.com/modernmedicine/Bladder%2C+Kidney%2C+and+Other+Urologic+Cancers/Cancer-patients-semen-is-preserved-late-used-littl/ArticleStandard/Article/detail/84515?contextCategoryId=9401&ref=25 San Antonio--A retrospective study of men with cancer who elected to cryopreserve
 their sperm because of cancer therapy found that 20% of men had already
 received one or more cycles of chemotherapy. The recognized toxic effects
 of chemotherapy and radiation on sperm cells make this a questionable practice 2004-02-01T05:00:00Z HTML http://www.modernmedicine.com/modernmedicine/News/Natural-conception-possible-after-varicocele-repai/ArticleStandard/Article/detail/84509?contextCategoryId=9401&ref=25 San Antonio--Repair of clinically significant varicoceles may result
 in nearly a 25% chance of natural conception, even in men who do not demonstrate
 significant improvements in their postoperative seminal parameters, according
 to University of Iowa researchers. 2004-02-01T05:00:00Z HTML http://www.modernmedicine.com/modernmedicine/Perspective/Varicocele-repair-offers-potential-to-help-inferti/ArticleStandard/Article/detail/84512?contextCategoryId=9401&ref=25 Varicocele is a common clinical finding, present in approximately 15%
 of adult men. When the patient with a varicocele visits a urologist, it
 is often due to testicular discomfort or fertility-related concerns. At
 the 2003 meeting of the American Society for Reproductive Medicine, both
 of these issues were addressed and are discussed in this issue of Urology
 Times. 2004-02-01T05:00:00Z HTML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Editorial/ArticleStandard/Article/detail/109096?contextCategoryId=9401&ref=25 IVF and birth defects: Evidence in favor of a urologic approach? 2004-02-01T05:00:00Z HTML http://www.modernmedicine.com/modernmedicine/Male+Infertility/Sperm-banking-An-essential-part-of-cancer-therapy/ArticleStandard/Article/detail/111980?contextCategoryId=9401&ref=25 In the 21st century, men should routinely be given the option of banking sperm prior to receiving cancer treatment that could impair their fertility. 2003-01-01T05:00:00Z HTML http://urologytimes.modernmedicine.com/urologytimes/Male+Infertility/Use-of-ICSI-on-the-rise-despite-stable-number-of-m/ArticleStandard/Article/detail/444489?contextCategoryId=9401&ref=25 The use of intracytoplasmic sperm injection has increased dramatically in the United States since 1995, while the proportion of patients receiving treatment for male-factor infertility has remained stable, according to a study in the New England Journal of Medicine (2007; 357:251-7). 0007-08-02T05:00:00Z http://urologytimes.modernmedicine.com/urologytimes/data/articlestandard/urologytimes/302007/444489null HTML