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    Prostate biopsy-related infections raise transfusion risk

    Infections that follow transrectal ultrasound (TRUS)-guided prostate biopsies are associated with an increased risk of blood transfusions and increased readmission following radical prostatectomy, even though the infections may have been clinically resolved well before the procedure was conducted, according to a study presented at the AUA annual meeting in San Diego.   

    Related: Transfusion’s effects examined in RP patients

    Paradoxically, the authors did not find a negative effect in the functional outcomes they analyzed. Results also showed that the risk of additional oncologic therapies was similar despite the presence of an infectious complication after prostate biopsy.

    "It may be that infectious complications affect the complexity of the case to increase blood transfusion rates following radical prostatectomy. But at the end, the proportion of the evaluated surgical complications was similar,” said first author Daniel Olvera-Posada, MD, of the Institute for Clinical Evaluative Sciences and the University of Western Ontario London, Ontario, Canada.

    "Using administrative data from the province of Ontario, we found that infectious complications significantly increased along the years of the study even though oncological and functional outcomes were similar. Physicians should inform patients who experience infectious complications following a prostate biopsy that although prostatectomy outcomes are similar, there is a slightly increased risk of the need for blood transfusion,” Dr. Olvera-Posada told Urology Times.

    Also see - VUR: What goes into parents’ treatment choices

    The study noted that no differences were found in the proportion of patients requiring adjuvant radiation, hormonal therapy, or surgical procedures to treat incontinence or erectile dysfunction. The 30-day post-op mortality was not affected. Outcomes were assessed in the first 12 to 24 months after radical prostatectomy.

    Next: Study findings

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