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    IC/BPS: One-fourth of patients have Hunner lesions

    Cystoscopy recommended in patients over age 50 and men, researcher advises


    Hunner lesions found in 27%

    Forty-one of 150 patients (27%) were found to have Hunner lesions. Those with Hunner lesions were about 15 years older on average than those without (57.3 vs. 42.3 years; p<.001). Those with Hunner lesions also reported less intense urologic pain scores (5.3 vs. 6.5; p=.021) as well as less bladder pain on the ICSI (3.0 vs. 3.5; p=.034) and increased nighttime frequency on the ICSI (3.5 vs. 2.6; p=.034).

    A lower percentage of patients with Hunner lesions had anxiety on the HADS (22.0% vs. 43.1%; p=.017), and a lower percentage had IBS (15.0% vs. 36.1%; p=.013).

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    There was no difference between the groups in daytime frequency, urgency, depression, fibromyalgia, and chronic fatigue syndrome.

    “I personally don’t find that patients have a lot of discomfort during cystoscopy. You may not want to do it in every single patient,” said Dr. Lai. “The older ones are probably more likely to be the ones in whom you’ll find Hunner lesions. I would suggest cystoscopy to look for Hunner lesions or other conditions in the differential diagnosis in patients over the age of 50, in men, or in those with hematuria or at risk for bladder cancer.”

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