• linkedin
  • Increase Font
  • Sharebar

    Genomic testing linked to higher surveillance uptake

    Persistence on AS also greater in men receiving testing with 17-gene assay, data indicate


    Results ‘durable out to 1 year’

    The utilization of AS in GPS-tested men increased, “and that result is durable out to 1 year. At 1 year, men who were tested with GPS were more likely to choose AS and stay on it than men who don’t have the benefit of the test,” Dr. Eure said.

    The higher utilization and persistence on AS resulted in a 21% absolute increase (34% vs. 55%) and a 62% relative increase in the proportion of GPS-tested men on AS at 1 year post-diagnosis compared with baseline. The net increase of patients on AS at 1 year was observed across age groups and racial groups.

    Read: Current prostate Ca guidelines miss germline variants

    “We thought we were maxed out on our AS acceptance but using GPS improved that,” said Dr. Eure. “The individual risk refinement provided by genomic testing demonstrates the impact of the GPS in identifying appropriate patients and supporting more AS decisions in clinically low-risk prostate cancer.”

    Dr. Eure is a consultant/adviser for Genomic Health, Inc. and has a financial or other relationship with several pharmaceutical companies. Several of his co-authors are employees of and have an investment interest with Genomic Health, and several co-authors have disclosures related to Genomic Health and/or pharmaceutical companies.

    More from Urology Times:

    RT-ADT combo may boost pN1 prostate cancer survival

    Prostate MRI-Bx may ID partial gland ablation candidates

    Fusion Bx-guided HIFU shows promise in localized PCa

    Subscribe to Urology Times to get monthly news from the leading news source for urologists.


    You must be signed in to leave a comment. Registering is fast and free!

    All comments must follow the ModernMedicine Network community rules and terms of use, and will be moderated. ModernMedicine reserves the right to use the comments we receive, in whole or in part,in any medium. See also the Terms of Use, Privacy Policy and Community FAQ.

    • No comments available