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    Fusion Bx-guided HIFU shows promise in localized PCa

    All patients completely continent at 6 months post treatment in Italian study

     

    Localization based on mpMRI, fusion Bx

    The procedures were performed at the urology unit of the INRCA Institute of Ancona in collaboration with the department of urology, Polytechnic University of the Marche Region of Ancona between November 2015 and April 2016. Cancer diagnosis and localization in all men was based on mpMRI and 3-D ultrasound-targeted fusion biopsy (Trinity) and standard biopsy. The HIFU platform uses software that directly imports the MRI/ultrasound imaging fusion and delivers the treatment to the intended targets. In order to immobilize the target lesions, the HIFU is performed under general anesthesia.

    Median operation time was 105 minutes (range, 80 to 180) and median HIFU exposure time was 70 minutes (range, 35 to 135).

    Median hospital stay was 3 days (range, 2 to 5 days). The catheter was removed within 7 days in 33 patients (80%) and kept in until day 15 in the remaining eight men.

    Read: Men must be entitled to PCa screening, treatment choice

    Postoperative complications included dysuria in nine men (22%) that was mild to moderate and resolved without any intervention after a median of 7 days. Five men (12.2%) developed a urinary tract infection.

    “There were no major complications in this series, and the median International Prostate Symptom Score, which was 8.2 at baseline, was not significantly changed at 6 months,” Dr. Milanese reported.

    The study had funding from the National Minister of Health, the Marche Region and Cariverona Bank.

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