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    Extended antimicrobial prophylaxis raises C. diff risk

    Better compliance needed with evidence-based approaches to post-op care

    Seattle—Whereas best practice policy states that antimicrobial prophylaxis for urologic procedures should be discontinued within 24 hours, extended regimens are common among patients undergoing surgery for urologic cancer and putting them at risk for hospital-acquired Clostridium difficile colitis, say researchers from the University of Washington, Seattle.

    RELATED: Are you satisfied with local infection prevention protocols?

    "A recent review indicates that the rate of C. difficile colitis has been increasing worldwide and points to increased antimicrobial use as a major contributing factor," said first author Joshua Calvert, MPH, a medical student at the University of Washington.

    “Our study demonstrates that inappropriate antimicrobial prophylaxis is exposing patients undergoing genitourinary cancer surgery to a preventable complication and one that is also a source of increased health care costs. These findings indicate a need for efforts that will improve provider compliance with evidence-based approaches to postoperative care.”

    NEXT: Quality collaboratives could help change surgeon behavior

    Antimicrobial prophylaxis, C. difficile infection

    Cheryl Guttman Krader
    Cheryl Guttman Krader is a contributor to Dermatology Times, Ophthalmology Times, and Urology Times.

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