• linkedin
  • Increase Font
  • Sharebar

    Endourology/Stones: Care utilization for stones growing rapidly in older adults


    • Good glycemic control in stone formers with diabetes reduced risk factors for uric acid calculi.

    • Differences in the upper urinary tract microbiome in urinary stone patients were strongly associated with patient age and stone type.

    • Limitations of sequencing platforms should be considered in microbiome studies of urologic diseases because different sequencing platforms can underestimate microbiome diversity and exhibit significant compositional differences.

    • Antibiotic treatment in rats affected the gut microbiome and was associated with increased urinary calcium excretion.

    • In another animal model, oxalate exposure exhibited broad stimulatory and inhibitory effects on the metagenome of the gut microbiome beyond just that of oxalate-degrading bacteria.

    • Prior antibiotic exposure was strongly associated with increased odds of incident kidney stones, and the greatest risk occurred with more recent and early life exposure.

    • Results of two randomized controlled trials showed no benefit for prolonged antibiotic use in patients at low risk for infection-related complications undergoing percutaneous nephrolithotomy (PCNL).

    • PCNL is a feasible alternative to nephrectomy to preserve ipsilateral renal function in select patients with xanthogranulomatous pyelonephritis, but postoperative infectious complications are common.

    • Outpatient PCNL is safe and feasible.

    • Physicians practicing at academic institutions or who are fellowship trained in North America or Europe are most likely to perform PCNL in patients on aspirin.

    Next: Continuing aspirin in patients undergoing PCNL


    You must be signed in to leave a comment. Registering is fast and free!

    All comments must follow the ModernMedicine Network community rules and terms of use, and will be moderated. ModernMedicine reserves the right to use the comments we receive, in whole or in part,in any medium. See also the Terms of Use, Privacy Policy and Community FAQ.

    • No comments available