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    Early fulguration may be best for radiation cystitis

    Length of stay is longer with late intervention or observation, data show

    TokyoEarly transurethral fulguration (TUF) may be a reasonable option for treatment of severe hemorrhagic radiation cystitis, according to Japanese urologists.

    In a retrospective study that included 283 patients hospitalized with grade 4 hemorrhagic radiation cystitis, the authors found using multiple analyses that patients treated by TUF early after admission (within 4 days) had a significantly shorter length of stay than patients treated by TUF 5 to 21 days after admission or who were managed conservatively with observation (no TUF within 21 days).

    Read—The urology match: Shaping the future of our field 

    “Despite its severity, there is very little evidence on the management of hemorrhagic radiation cystitis. The findings of our study support early intervention with TUF,” said first author Toru Sugihara, MD, MPH, assistant professor of urology at the University of Tokyo.

    The patients included in the study were identified from the Japanese national hospitalization database as being hospitalized during the years 2007 to 2012 for radiation cystitis and receiving a transfusion within 3 days of admission. Of the 283 patients, 65 (23%) received TUF within 4 days of admission, 32 (11.3%) were treated by TUF between days 5 and 21 post-admission, and 186 (65.7%) patients did not receive TUF within the first 21 days after they were hospitalized.

    Next: Shorter median LOS early group


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