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    Cryo most cost-effective fertility preservation strategy

     

    The cryopreservation costs used—$402 for an initial fee and $343/year—were based on published fees from commercial sperm cryobank companies. Sensitivity analyses considered microTESE costs ranging from $3,000 to $11,000 and sperm banking durations between 2 and 10 years.

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    Azoospermia rates after chemotherapy and radiation therapy were 18% and 6%, respectively. For the radiation therapy analysis, cryopreservation was consistently more cost-effective than microTESE for all scenarios, regardless of the number of years banked or cost of microTESE. For the chemotherapy group, cryopreservation was the more cost-effective alternative except in analyses using highly discounted costs for surgical sperm extraction that are probably unrealistic, Dr. Mehta told Urology Times.

    “Results of our sensitivity analyses favored microTESE only when its cost was in the $3,000 to $5,000 range,” he said. “More typically, however, the cost is in the $8,000 to $10,000 range for total out-of-pocket expenses. After adding in the cost of IVF, which is between $12,000 and $15,000 per cycle, sperm banking is far more cost-effective, no matter the duration, and despite the lower success rate of IUI for cryopreserved sperm compared with IVF/ICSI for surgically extracted sperm.”

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