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    Robotic RP associated with improved margin status

    Robot-assisted technique also linked to decreased need for ADT, post-RP radiation

    Orlando, FL—Robot-assisted radical prostatectomy (RARP) may be associated with improved surgical margin status compared to open radical prostatectomy (ORP) for men with intermediate-risk and high-risk prostate cancer, according to a study presented at the AUA annual meeting in Orlando, FL.

    Researchers also found that RARP was associated with a decreased need for androgen deprivation therapy (ADT) or radiotherapy post-prostatectomy compared to ORP.

    Maxine Sun, MDDr. Sun“This represents the first study to show that RARP may have some long-term oncological benefit compared to ORP, using surgical margins as a correlate. Previous studies from tertiary care centers were mostly inconclusive and lack generalizability,” said senior author Maxine Sun, MD, co-director of the Cancer Prognostics and Health Outcomes Unit in the department of urology at the University of Montreal Health Center in Montreal.

    Exaggerated marketing claims and higher upfront costs have been among the barriers to clinicians adopting robotic technology. In addition, few clinically significant benefits have been shown when RARP is compared to ORP.

    In the current study, researchers from several institutions analyzed Surveillance, Epidemiology, and End Results data and identified 5,556 patients treated with RARP and 7,878 treated with ORP between 2004 and 2009. The authors conducted propensity-based analyses to minimize treatment selection biases and used generalized linear regression models for comparison of radical prostatectomy surgical margin status and use of additional cancer therapy by surgical approach. Mean patient age was 69 years, and 85% were Caucasian.

    Robotic vs. open RP: Oncologic outcomes

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