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Hot Topics in Prostate Cancer

Newer agent efficacious in non-metastatic castration-resistant PCaAdding apalutamide prior to metastases may benefit men with prostate cancer who are no longer responding to androgen deprivation therapy, according to new phase III study findings.
Chemo improves QoL in men with non-metastatic, metastatic PCaDocetaxel (Taxotere) appears to help improve overall quality of life and delay time for subsequent therapy in men with both non-metastatic and metastatic prostate cancer, according to a new analysis of STAMPEDE trial results.
ADT+EBRT improves OS in men with post-RP LN metastases"While improving local control seems to be important, especially in those with high-risk features, it’s not clear whether adjuvant EBRT is necessarily better than early salvage EBRT," writes Badar M. Mian, MD.
Genetic testing for prostate Ca: What the experts sayA recently published statement provides an evidence-based, consensus-driven framework on the role of genetic testing for determining prostate cancer risk, screening, and management.
Liquid biopsy tests for prostate Ca show low congruenceThe findings “[raise] the specter that patients could potentially receive different treatments depending on the cell-free DNA platform,” authors of a recent research letter write.
Biennial vs. annual prostate biopsies: What the data showAmong men undergoing active surveillance for low-risk prostate cancer, biennial biopsies appear to be an acceptable alternative to annual biopsies.
Prostate Ca test linked to reduction in biopsiesPatients with non-suspicious digital rectal exam findings and total PSA in the 4.0- to 10.0-ng/mL range are far less likely to be biopsied if they’ve undergone Prostate Health Index (phi) testing than if they don’t.
PSA screening: What do you tell primary care docs?We asked several urologists about whether they advocate for PSA screening to primary care physicians in their area.
Pair of genes may predict prostate cancer metastasisOverexpression of a specific pair of genes might provide early warning of prostate cancer patients’ likelihood of progressing to metastatic disease.
Why you need to better counsel PCa patients on sexual functionThere’s a troubling disconnect between low-risk prostate cancer patients’ desire to preserve sexual function and the treatment choices they and their doctors often make.