Wayne Kuznar
Wayne Kuznar is a contributor to Urology Times.
AS success rate strong in appropriate PCa patients
Large study examines surveillance results in men with very low-, low-, intermediate-, and high-risk disease.
Modalities for high-risk PCa yield similar outcomes
Treatment options for high-risk prostate cancer perform similarly. In a single-institution study, radical prostatectomy was associated with worse biochemical failure, less clinical failure, and superior prostate cancer-specific mortality compared with radiation therapy and brachytherapy, reported Jay P. Ciezki, MD, at the 2016 Genitourinary Cancers Symposium in San Francisco.
Salvage HIFU shows promise in post-RT PCa patients
High-intensity focused ultrasound as salvage therapy allows for intermediate-term disease control in selected patients with recurrence following radiation therapy for prostate cancer.
No link between PDE-5 use, prostate Ca recurrence
No significant relationship was found between use of a phosphodiesterase type-5 inhibitor and prostate cancer recurrence after treatment in a nested case-control study.
Greater long-term side effect risk with intermittent ADT
In men with metastatic prostate cancer, those assigned to intermittent androgen deprivation therapy have more ischemic and thrombotic events than those assigned to continuous androgen deprivation, according to Columbia University researchers.
New guideline broadens criteria for surveillance
New clinical practice guidelines for the management of prostate cancer from the National Comprehensive Cancer Network expand the number of patients who may be considered for active surveillance to those with favorable intermediate-risk prostate cancer.
Sunitinib vs. everolimus: PFS, toxicity differ in study
In a head-to-head comparison, sunitinib (Sutent) prolonged radiographic progression-free survival compared with everolimus (Afinitor), but with greater toxicity, in patients with specific subtypes of metastatic renal cell carcinoma and non-clear cell histology, said Andrew J. Armstrong, MD, MSc.
C-11 choline PET, pMRI identify recurrence patterns
C-11 choline positron emission tomography and multiparametric pelvic magnetic resonance imaging (pMRI) can be used successfully to identify recurrence patterns in patients with biochemical recurrence after radical prostatectomy.
Micro subinguinal varicocelectomy found efficacious
Microscopic subinguinal varicocelectomy results in improvement of multiple semen parameters, with a natural pregnancy rate of 34% and an overall pregnancy rate of approximately 63%.
Concomitant Ra 223, abiraterone found safe, effective
Radium 223 dichloride (Ra 223 [Xofigo]) can be safely combined with abiraterone acetate (ZYTIGA) for the treatment of patients with metastatic castration-resistant prostate cancer with symptomatic bone metastases, and appears to result in decreased bone pain and improved quality of life, according to the interim results of an open-label prospective study known as eRADicAte.